SPINA TeamAnother study highlights advantages of SPINA-GBeta over the #HOMA method, here with correlation to the adherence of #mediterranean diet.
#SPINA_Carb #SPINA-GBeta #SPINA-GR #SPINA-DI
Gestational #diabetes mellitus (GDM) is linked to significant adverse outcomes for both mothers and their offspring. Since #SPINA-GBeta outperforms #HOMA-Beta, its use is advised as a preferred calculated biomarker for the evolution and pathophysiology of #GDM.
#SPINA_Thyr and #SPINA_Carb, two implementations of the structure parameter inference approach (SPINA), provide evidence-based improved methods for diagnosis and endotyping of endocrine diseases. Now, thoroughly tested apps for Mac and Windows are available for free download.
SPINA Carb 5.1.0 Cyclone has been released in its final version.
#SPINA_GBeta #SPINA_GR #SPINA_-DI #SPINA_Carb #insulin #glucose #homeostasis #prediabetes #diabetes
https://sourceforge.net/projects/spina/files/SPINA%20Carb/
Release candidate 3 for the software SPINA Carb Cyclone is available for macOS, Windows and Linux.
https://sourceforge.net/projects/spina/files/SPINA%20Carb/
https://doi.org/10.5281/zenodo.15249620
Release candidate 2 of #SPINA_Carb is available for testing.
https://sourceforge.net/projects/spina/files/
After intensive internal testing, the release candidate 1 of the #SPINA_Carb app is available. This is the "sister" app for #SPINA_Thyr, and it is provided for purposes of testing.
https://sourceforge.net/projects/spina/files/
#SPINA_Carb has high discriminatory power for the distinction between #diabetes and normal glucose homeostasis. SPINA-GBeta is better than HOMA-Beta, SPINA-GR is better than HOMA-IR and QUICKI, but SPINA-DI is best, being even more powerful than ivGTT. https://pubmed.ncbi.nlm.nih.gov/38169110/
A novel simple disposition index (SPINA-DI) from fasting insulin and glucose concentration as a robust measure of carbohydrate homeostasis - PubMed
SPINA-DI is a novel simple reliable and inexpensive marker of insulin-glucose homeostasis suitable for screening purposes and a wider clinical application.