StructBiolCommunicationsThis Methods Communication describes an in situ diffraction measurement system that can collect small-wedge data from crystals in a drop on a plate at room temperature #ProteinCrystallography #InSituXRayDiffraction #RoomTemperatureDataCollection https://doi.org/10.1107/S2053230X22005283
In situ crystal data-collection and ligand-screening system at SPring-8
An in situ X-ray diffraction measurement system using a crystallization plate has been constructed at the SPring-8 protein crystallography beamline. Utilizing small-wedge measurements and incorporating a liquid dispenser to prepare protein–ligand complex crystals, this system will make ligand screening possible.