I hope my set of #RedemptionWeek threads on #ClinicalTrials and #Methodology has been in some way useful to a couple of people. It’s certainly been cathartic for me.

6/6

A bonus following my #RedemptionWeek:
I’m highlighting a short paper that can be used for teaching caution in #ClinicalTrial subgroups:
“‘Thursday’s child has far to go’—interpreting subgroups and the #STAMPEDEtrialhttps://www.annalsofoncology.org/article/S0923-7534(19)34965-8/fulltext

1/6

I’ll be back to wrap up my (rather stretched out) #Methodology #ClinicalTrials #RedemptionWeek

11/11

Day 5 #RedemptionWeek for #ClinicalTrials #Methodology returns to Healthcare Systems Data for #ClinicalTrials.
“Realising the full potential of data-enabled trials in the UK: a call for action” summarised a positive, national workshop from HDRUK, NIHR + CPRD
1/11
Day 4 of #ClinicalTrials #Methodology #RedemptionWeek highlights the value (or lack of it) of retrospective data validation and source data verification (SDV) for certain aspects of trials.

Day 3 #RedemptionWeek for #ClinicalTrials #Methodology papers focuses on oversight of #ClinicalTrials.

Robust clinical trial oversight is critical to the validity
and safety of trials. Clear oversight structures benefit trials.

1/12

On Day 3 of #RedemptionWeek, we’ll talk about trial oversight.

5/5

On Day 2 #RedemptionWeek, I share our review of healthcare systems data (HSD; sometimes called routinely-collected healthcare data – RCHD), for clinical trials in the UK, led by @SarahLensen
#routinedata #healthdata

#clinicaltrials #methodology

1/5

On (Mastodon) #RedemptionWeek Day 2, I'll talk about healthcare systems data or #RCHD
It’s #RedemptionWeek (on Mastodon) in which I’m highlighting 5 #methodology papers I’ve co-authored that you might have missed.
First up: ”How do you design randomised trials for smaller populations? A framework”with Tim Morris and Max Parmar