R ConsortiumMay 28

New from the R Consortium nlmixr2 Working Group:

The nlmixr2 Working Group is expanding what open-source R tooling can support in pharmacometrics, including time-to-event modeling workflows that are important in clinical and drug-development settings.

This new post highlights technical work from Justin Wilkins and the nlmixr2 Development Team on fitting parametric time-to-event models in nlmixr2.

Read more:
https://r-consortium.org/posts/survival-analysis-with-nlmixr2/

#RStats #Pharmacometrics #PKPD #ClinicalResearch #OpenSource

LED3hubJun 19, 2025
The first #FlashTalk session of the #LED3Symposium gave us insights into early #PKPD modelling for predicting the outcome of clinical studies for #tuberculosis treatment (Asina Gijasi) and into self-encoded libraries for affinity-selection MS of macrocyclic compounds (cycloSELs, Miguel Mata).
Joserra PañoDec 24, 2022

Subcutaneously administered #antibiotics: a review

via Journal of Antimicrobial Chemotherapy

#PKPD

https://academic.oup.com/jac/article-abstract/78/1/1/6827323

Subcutaneously administered antibiotics: a review

AbstractBackground. Subcutaneous (SC) administration of antibiotics represents an attractive alternative to the intravenous (IV) route.Methods. We performed a s

OUP Academic
Mathieu DesgroseilliersNov 14, 2022

#introduction 👋

I am a French 🇨🇦 clinical #criticalcare #pharmacist from Montreal with interest in #sedation #analgesia #delirium #hemodynamic #pkpd #teamwork

I am co-founder of the French Critical Care podcast FrancoFOAM https://francofoam.com/ & I'm part of the amazing team of EZDrips https://www.ezdrips.com/ a drug administration facilitating app.

Here to continue learning on critical care & other stuff !

FrancoFOAM - Communauté francophone en soins critiques

FrancoFOAM est une communauté francophone indépendante de mordus en soins critiques. Mission : faire connaître et promouvoir le travail en soins critiques

FrancoFOAM
Show threadJustin WilkinsNov 8, 2022
What this boils down to is using mathematical/statistical models to help explain and predict what the body does to the drug (#Pharmacokinetics, #PK) and what the drug does to the body (#Pharmacodynamics, #PD) - these are often combined to produce #PKPD or #ExposureResponse models.