🚨 New Publication in @Journal_Infect
📍 Discussion on Reemergence of Oropouche virus (OROV) in Ecuador, 2024: molecularly confirmed cases in Bolívar, Los Ríos & Morona Santiago—outside known vector zones. A call for expanded surveillance!
🔗 https://doi.org/10.1016/j.jinf.2025.106544
#OROV
#Oropouche Virus (OROV) in #Pregnancy: An Emerging Cause of #Placental & #Fetal #Infection Associated with #Stillbirth & #Microcephaly following Vertical Transmission, Viruses: https://www.mdpi.com/1999-4915/16/9/1435
This communication examines biology, epidemiology, & clinical features of #OROV, summarizes the 2023–24 epidemic, & describes reported cases of vertical transmission & #congenital infection, fetal death, and #microcephaly in pregnant women with Oropouche fever,...
Oropouche virus (OROV) is an emerging arbovirus endemic in Latin America and the Caribbean that causes Oropouche fever, a febrile illness that clinically resembles some other arboviral infections. It is currently spreading through Brazil and surrounding countries, where, from 1 January to 1 August 2024, more than 8000 cases have been identified in Bolivia, Brazil, Columbia, and Peru and for the first time in Cuba. Travelers with Oropouche fever have been identified in the United States and Europe. A significant occurrence during this epidemic has been the report of pregnant women infected with OROV who have had miscarriages and stillborn fetuses with placental, umbilical blood and fetal somatic organ samples that were RT-PCR positive for OROV and negative for other arboviruses. In addition, there have been four cases of newborn infants having microcephaly, in which the cerebrospinal fluid tested positive for IgM antibodies to OROV and negative for other arboviruses. This communication examines the biology, epidemiology, and clinical features of OROV, summarizes the 2023–2024 Oropouche virus epidemic, and describes the reported cases of vertical transmission and congenital infection, fetal death, and microcephaly in pregnant women with Oropouche fever, addresses experimental animal infections and potential placental pathology findings of OROV, and reviews other bunyavirus agents that can cause vertical transmission. Recommendations are made for pregnant women travelling to the regions affected by the epidemic.
R to @ECDC_EU: The risk of human exposure to OROV in the EU/EEA is considered VERY LOW, despite the likely importation of further #OROV disease cases, as the competent vectors are absent from continental Europe.
Read more: https://bit.ly/3yzj2Yu
#Oropouche
[2024-08-12 18:13 UTC]
According to the ECDC Threat Assessment Brief on Oropouche virus (OROV) disease published today, between June and July 2024, 19 imported cases of OROV disease have been reported for the first time in European Union (EU) countries, all linked to travels in Cuba and Brazil.
R to @ECDC_EU: The risk of #OROV infection for citizens travelling to or residing in epidemic areas in South & Central America & the Caribbean is moderate.
The risk increases for those visiting highly affected areas, particularly in northern Brazil or the Amazon region.
https://bit.ly/3WXWaeq
[2024-08-12 18:13 UTC]
R to @ECDC_EU: #OROV is mainly transmitted by the Culicoides paraensis midge, which is widely distributed in the Americas but absent in Europe. Several species of mosquitoes are also possible vectors of the virus.
[2024-08-12 18:13 UTC]
According to the ECDC Threat Assessment Brief on Oropouche virus (OROV) disease published today, between June and July 2024, 19 imported cases of OROV disease have been reported for the first time in European Union (EU) countries, all linked to travels in Cuba and Brazil.
R to @ECDC_EU: in June and July 2024, 19 imported cases of #OROV disease were reported for the first time in EU, all linked to travel in Cuba or Brazil.
Over 8 000 cases have been reported in South America, Central America and the Caribbean since January 2024.
[2024-08-12 18:13 UTC]
#PAHO epidemiological alert: #Oropouche in the Americas. Mother-to-child transmission reported, possible link to fetal loss and microcephaly
https://www.paho.org/en/documents/epidemiological-alert-oropouche-region-americas-1-august-2024
Considering the increase in reported cases of Oropouche in 2024, including in areas in which no cases had been historically recorded, as well as the identification of fatal cases associated with Oropouche virus (OROV) infection and possible cases of vertical transmission of the virus and its consequences, the Pan American Health Organization / World Health Organization (PAHO / WHO) urges Member States to strengthen surveillance and implement laboratory diagnosis for the identification and characterization of cases, including fatal cases and vertical transmission p
Dr Alfonso J Rodriguez-Morales
daniel campion
Giuseppe Michieli
ECDC
daniel