Mastodawn

conscientious objector 🇨🇭🪂🤓🕊️🖖Nov 29, 2023

Kann man nicht oft genug wiederholen.

Wer mit Viren leben will soll sich bitte zur Fledermaus 🦇 weiterentwickeln!

https://fediscience.org/@PLOSBiology/111493091544782096 The human #OAS1 protein restricts #SARSCoV2 replication, but #HorseshoeBat OAS1 has lost this ability. @spyroslytras @WilsonLabCVR &co resurrect the 60,000,000 yr old ancestral bat OAS1, revealing how this ancient #antiviral mechanism was lost #PLOSBiology https://plos.io/3N6fWPx #corona

PLOS Biology (@[email protected])

Attached: 1 image The human #OAS1 protein restricts #SARSCoV2 replication, but #HorseshoeBat OAS1 has lost this ability. @spyroslytras @WilsonLabCVR &co resurrect the 60,000,000 yr old ancestral bat OAS1, revealing how this ancient #antiviral mechanism was lost #PLOSBiology https://plos.io/3N6fWPx

FediScience.org

PLOS Biology Nov 29, 2023

The human #OAS1 protein restricts #SARSCoV2 replication, but #HorseshoeBat OAS1 has lost this ability. @spyroslytras @WilsonLabCVR &co resurrect the 60,000,000 yr old ancestral bat OAS1, revealing how this ancient #antiviral mechanism was lost #PLOSBiology https://plos.io/3N6fWPx

Resurrection of 2′-5′-oligoadenylate synthetase 1 (OAS1) from the ancestor of modern horseshoe bats blocks SARS-CoV-2 replication

The human OAS1 protein restricts SARS-CoV-2 replication, but the horseshoe bat OAS1 has lost this ability. This study reconstructs the functional 60-million-year-old OAS1 protein ancestral to all horseshoe bats, and reveals how this ancient antiviral mechanism was lost in the bats.