@SunnJax This is exactly why all junctions should be *physically* constructed so that drivers have to make a right-angle turn, not a swerve, and will see all "obstacles" (people) before their vehicle
#RoadSafety #Junctions #PeopleOnBicycles #Walkers #Trucks #SUVs

New paper from the Zerial Lab!

My colleagues and I have shown that apical projections across the bile canaliculi are load-bearing structures. These structures contribute to sustaining the anisotropic #growth of the nascent tube under increased intraluminal #pressure during #liver #development. These structures are supported by adherens #junctions and sealed by tight junctions.
I believe only @nunopmartins is here but if I am mistaken please tag any other author.
#CellPolarity #CellBiology #actomyosin #tubulogenesis

https://rupress.org/jcb/article/222/4/e202208002/213840/Hepatocyte-apical-bulkheads-provide-a-mechanical

Hepatocyte apical bulkheads provide a mechanical means to oppose bile pressure | Journal of Cell Biology | Rockefeller University Press

Bebelman and Bovyn et al. demonstrate that apical bulkheads, connections between the apical membranes of opposing hepatocytes, are load-bearing mechanical eleme