PLOS BiologyHow does the #RedBloodCell band 3 #IonTransporter work? This study uses several #cryoEM structures of #band3 in different conformations to reveal that the ion transport mechanism involves the concerted movement of Cl- and HCO3- ions #PLOSBiology https://plos.io/4dRKAqZ
Cryo-EM structures of the human band 3 transporter indicate a transport mechanism involving the coupled movement of chloride and bicarbonate ions
Previous studies have solved the high-resolution structures of the dimeric band 3 transporter, but the ion transport mechanism has not yet been fully elucidated. This study solves several cryo-EM structures of band 3 in different conformations indicating that the ion transport mechanism involves the concerted movement of chloride and bicarbonate ions.