Now in issue for IOB!

Does the #Glucocorticoid #Stress Response Make #Toads More #Toxic?
An Experimental #Study on the Regulation of #Bufadienolide #Toxin #Synthesis
by
Üveges, Kalina, Szabó, Móricz, Holly, Gabor, Hettyey, & Bókony

https://doi.org/10.1093/iob/obad021

#science #amphibian #biology

Does the Glucocorticoid Stress Response Make Toads More Toxic? An Experimental Study on the Regulation of Bufadienolide Toxin Synthesis

Synopsis. Chemical defense is a crucial component of fitness in many organisms, yet the physiological regulation of defensive toxin synthesis is poorly understo

OUP Academic

IOB

“ We investigated if #cortisol, the primary circulating #glucocorticoid in #teleosts, could be extracted from #stickleback #dermal bone and quantified using a commercially available #enzyme immunoassay (EIA)."

by Dillon , Witten & Buck

https://doi.org/10.1093/iob/obad007

Evaluating Dermal Bone as a Novel Source of Endocrine Information in Ninespine and Threespine Stickleback Fish

Synopsis. Monitoring the physiology of small aquatic and marine teleost fish presents challenges. Blood samples, often the first choice for endocrinologists, ca

OUP Academic
Great news, so happy to have contributed here, thanks to #EvaEstebanez from #UB for many years of great interactions. If you want to know about the #functional plasticity of #glucocorticoid receptor check this cake just out from the oven —-> https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkac1119/6858817
multivalency of the glucocorticoid receptor ligand-binding domain explains its manifold physiological activities

Abstract. The glucocorticoid receptor (GR) is a ubiquitously expressed transcription factor that controls metabolic and homeostatic processes essential for life

OUP Academic
Dysregulation of hypothalamic–pituitary–adrenal axis and #glucocorticoid system, and influence of different versions of the serotonin transporter and 5-#HT1A receptor genes may influence the development of #neuroticism in combination with environmental effects