For evolutionary biologists interested in tracing genomes back to their ancient ancestors, we’ve developed EdgeHOG—a tool that reconstructs ancestral gene orders at an unprecedented scale and speed. #Genomics #EvolutionaryBiology #EdgeHOG
For instance, we can identify very highly conserved adjacencies corresponding to histone clusters (arrow) or fast evolving sex chromosomes.
Check out first author Charles Bernard‘s blog post here: https://lab.dessimoz.org/blog/2024/08/30/edgehog
Preprint: https://www.biorxiv.org/content/10.1101/2024.08.28.610045v1
