The number of instances of a Pfam within a #genome shows the same trend (shown in last toot). This matches #DifferentialDiversification below, shaping the #evolution of #proteome content via how many paralogous copies a given sequence ends up in. 7/11

#DifferentialDiversification can explain long-term trends in body size (Cope's rule) https://www.science.org/doi/10.1126/science.1260065. 4/11