#Phosphoproteomics reveal pervasive rewiring of #Cdk1 and Polo kinase phosphorylations during yeast #meiosis, ensuring the occurrence of two successive divisions without intervening S-phase

Lori Koch, Adele Marston et al

https://www.embopress.org/doi/full/10.1038/s44318-024-00059-8

"CDK1, in the white room, with the E3 ligase", a tetraptrych in the Dark Proteome series. #darkProteome #CDK1

Want Erk-cellent representation of Erk signalling dynamics?

Scott G. Wilcockson and colleagues #AmoyelLab #HillLab explore an improved #biosensor that faithfully reports #Erk activity without being impacted by #Cdk1.

First #preLight from Sakurako Kobayashi #PeterMac:

📜 https://prelights.biologists.com/highlights/an-improved-erk-biosensor-reveals-oscillatory-erk-dynamics-driven-by-mitotic-erasure-during-early-development/