I hope everyone's watching #CancerDetectives on Channel 4!
My team has sweated over various aspects of this. It's a big passion project, my colleague's second baby, and hopefully will help more people understand what it means to do #CancerResearch today, and indeed what it means to have cancer now, compared to some decades ago.

#channel4 #cancer #cancerVaccines #BrainTumours #LiquidBiopsy #cancerOfUnknownPrimary #LungCancer #P53 #liFraumeni #5GTrial #MILITrial #DETECTION2Trial #CancerResearchUK

Genetic changes sustaining the development of #CancerOfUnknownPrimary (CUP) remain elusive. New study reports a novel activating mutation of the #AxonGuidance gene #PLXNB2 that sustains proliferative autonomy and confers invasive properties to CUP stem cells, in EGFR-dependent manner.

By E. Giraudo, L. Tamagnone & colleagues

👉 https://doi.org/10.15252/emmm.202216104