#Parkinson’s disease drug may help teens with type 1 diabetes
Drug improves blood pressure, vessel characteristics.
My newest news story in the #MedicalPost/ #CanadianHealthcareNetwork.
Sorry --it's password protected for Canadian #doctors, #pharmacists. But here are some highlights:

DEC 2022 -- Bromocriptine, a medication used to treat Parkinson’s disease and as an adjunct treatment for type 2 diabetes (T2D), can lower blood pressure in teens with type 1 diabetes (T1D).

Increased blood pressure in teens is a concern because it raises the risk of cardiovascular events later in life. Peripheral vascular dysfunction, along with accelerated large arterial stiffness and impaired cardiac function, has already been shown in youth with T1D, according to a study in Hypertension.

A once-daily AM bromocriptine quick release (BCQR) formulation was developed and FDA approved for therapeutic use in adults with type 2 diabetes (T2D), the study said. Previous research showed it was associated with a reduction in major adverse #cardiovascular (CV) events in patients with T2D after one year of treatment....

#MedMastodon #diabetes #cardiovascular #cardiology
Link to the story: https://www.canadianhealthcarenetwork.ca/parkinsons-disease-drug-may-help-teens-type-1-diabetes

Link to the study: https://pubmed.ncbi.nlm.nih.gov/36472197/

Eating grapes increases UV protection in skin, reduces, melanoma risk, study finds. But some foods increase the risk of photodamage. My newest news story in the #MedicalPost/ #CanadianHealthcareNetwork.
Sorry --it's password protected for Canadian #doctors, #pharmacists. But here are some highlights:

DEC 2022 -- Does eating grapes each day help keep the melanoma away?

The answer is yes—at least in people with specific characteristics, according to a study in Antioxidants. There, researchers investigated skin changes in people who consumed grapes daily. In fact, grapes appear to reduce risk by altering some of the gut microbiome and increasing resistance to ultraviolet (UV) irradiation of the skin

Looking specifically at grapes was of interest for several reasons. For one, grapes are a common source of resveratrol, a cancer chemopreventive agent found in wine and grape juice, as well as having hundreds of phytochemicals. In general, studies have suggested grape consumption has an influence on atherosclerosis, inflammation, cancer, gastrointestinal health, central nervous system effects, osteoarthritis, urinary bladder function, and vision, the authors wrote.

Some studies (mostly in mice, but also some small human trials) have shown photoprotection activity of the skin from consuming grape powder. One study showed “enhanced DNA damage repair, reduced proliferation, increased apoptosis, and modulation of oxidative stress markers,” the paper said.
The cross-over study by Dr. John Pezzuto from Western New England University in Massachusetts and colleagues was conducted to investigate the potential of grape consumption to modulate UV-induced skin erythema...
... Other studies in the medical literature show various foods which can increase photoprotection, while some can lead to increased photodamage.

A review of plant-based foods and skin health identified several beneficial fruits and vegetables. Researchers noted “each food has a unique nutrient profile that provides an array of bioactive compounds that either alone or synergistically may afford protection for the skin,” and that “diets consisting mainly of meat, refined grains, snacks, soft drinks, coffee, and alcoholic beverages were associated with more wrinkling in women.”

“Overall, we found that the consumption of colorful fruits and vegetables abundant in vitamins, carotenoids, anthocyanins, and polyphenols is indicated for skin health and esthetics. In general, yellow, orange, and red fruits such as mangos, melons, citrus, tomatoes, and vegetables such as red bell peppers and dark-green leafy kale are good sources of carotenoids. Fruits with deep red or purple colors such as grapes, pomegranate, and passion fruit are rich in anthocyanins and polyphenols,” the paper said. ...

#MedMastodon #dermatology
https://www.canadianhealthcarenetwork.ca/eating-grapes-increases-uv-protection-skin-reduces-melanoma-risk?check_logged_in=1