Uniter 2. Why is #CD7 such an important race? 3/6 🎥 Stefania Colosimo #NJ7
The coverage diagrams for T-cell v. urine observations of #CD7:p show a number of characteristic differences. The observations in blood plasma conform to the T-cell pattern, suggesting that the concentration of the soluble form in blood is below its LOD in typical proteomics experiments. Probably just another sad consequence of the knee-jerk application of convenient-but-poorly-thought-out FASP methods.

This type I membrane protein prefers to adorn T-cells, sampling the environment with a single immunoglobulin-like fold. Signal peptide: (1-25); extracellular region: (26-177); TM domain (178-200); intracellular Y-phospho-IDR (201-240). The soluble form found in urine has no signals cward of R148 & an internal cut at L130-V131.

Human cluster of differentiation member 7 (#CD7:p)―HPA mRNA tissue + cell type distributions & GPMDB protein tissue + cell type tabbulations. #proteomics #sources_sinks