To fully realize the potential of our clinical trials, we must go beyond randomization, and use causal inference and pharmacometric modelling and simulation. Advancing both we show that non-linear mixed effects modelling implements the equivalent of standardization in causal inference. Dive into this if you're into #causal #causalinference #DAGs #pharmacometrics, or clinical development #stats.
Another pharmacometrics #rstats post, this time about running simulations with mrgsolve