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We work on gene regulation in cancer and cell differentiation. Focus on nucleosome positioning, chromatin organisation, transcription factor binding, CTCF, cell-free DNA (cfDNA).

This account will be mostly about things of interest to our lab (run by the PI, Vlad Teif). For a community-focused account see @generegulation.

You may be also interested in our bots @nucleosome_bot, @TFbinding_bot, @CTCF_papers

Web sitehttps://generegulation.org
Twitterhttps://twitter.com/TeifLab
Publicationshttps://scholar.google.com/citations?user=cUot9vwAAAAJ
We had a cake today :)
RT @leo_schalkwyk
Congratulations to @yucheng62950120 on his successful viva and thanks to examiners @teiflab and @ChloeCWong !
Excited to present our new preprint on nucleosome reorganisation in breast cancer! https://www.biorxiv.org/content/10.1101/2023.04.17.537031v1 It's a large project, mapping nucleosome repositioning in paired normal and tumour tissues and cell-free DNA from the same patients #TFbinding #cfDNA #H1X #5mC #LiquidBiopsy
RT @FMP_lab
pls RT: New #postdoc position: Ever wondered how aging deteriorates the functioning of our genome? Here, we use genomics & genome engineering to dissect the decline of structure & function of the genome during cellular senescence. Get in touch: [email protected]
The cat's name is Cheshire and the squirrel's name is unknown (yet). They've been friends for a while. Photo by my brother.
Happy New Year, friends! Let 2023 be a better year! We wish you health, strength, happiness, peace, and success!

Our new preprint! Nucleosome repositioning in chronic lymphocytic leukaemia https://www.biorxiv.org/content/10.1101/2022.12.20.518743v1
▶️Nucleosome changes at few sensitive regions allow patient stratification
▶️Nucleosome repeat length decreases with cancer aggressiveness
▶️Interplay with methylation, TFs and more!

🐦🔗: https://twitter.com/generegulation/status/1605590427142213633

RT @[email protected]

New preprint! Nucleosome repositioning in chronic lymphocytic leukaemia https://www.biorxiv.org/content/10.1101/2022.12.20.518743v1
▶️Nucleosome changes at few sensitive regions allow patient stratification
▶️Nucleosome repeat length decreases with cancer aggressiveness
▶️Interplay with methylation, TFs and more!

🐦🔗: https://twitter.com/generegulation/status/1605590427142213633