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Associate Prof. of Biological Sciences @ Columbia University

Glad to have the pLSM light sheet microscopy work out now in Nature Biomedical Engineering!
https://www.nature.com/articles/s41551-024-01249-9

pLSM framework is essentially about making cutting-edge light sheet microscopy capabilities broadly accessible, at a small fraction of cost with highly simplified mechanical, optical and computational footprints. We are also hard at work to further streamline ways to get the system in the hands of interested users fast - more on that soon.

Youtube: https://www.youtube.com/playlist?list=PLXQ8jqcqgW9DVrepPeLzAHwnEqtsX-N7M

Low-cost and scalable projected light-sheet microscopy for the high-resolution imaging of cleared tissue and living samples - Nature Biomedical Engineering

A light-sheet fluorescence microscope leveraging consumer-grade components as well as optimized optics and software facilitates the high-resolution imaging of cleared and living samples at scale with lower costs.

Nature

Happy to introduce our latest gizmo from the lab: pLSM !
https://www.biorxiv.org/content/10.1101/2023.05.31.543173v1

A big shoutout to our brilliant grad student, Yannan Chen, who led this work.

In short, pLSM is a plug-and-play, cost-effective and easy-to-scale light sheet microscopy platform. More than 20 times cheaper, with imaging quality comparable to high-end systems.

https://github.com/tomerlab/pLSM-Control

#LSFM #preprint #biorxiv #lightsheet #dopamine

Once a microscopist, always a microscopist 🤓. Took this picture at Niagara Falls this weekend, showing macro refractive index change boundary marked by rainbow.