Happy to see our News & Views published in Nature Chemistry, written with postdoc in the lab Chris Watkins, about two new papers from Lei Wang’s @UCSF on their sulfur(vi) fluoride exchange (SuFEx)-based chemical crosslinking methods – useful for RNA-protein and glycan-protein interactions!

https://doi.org/10.1038/s41557-022-01116-7

Nucleolar DDX21 is sensitive to [glucose], where high [Glc] results in splitting of DDX21 dimers, nucleolar exit, finally leading to modulation of splicing (examined in epidermal differentiation models)

By Weili + Douglas in Paul Khavari's lab @Stanford Med

happy I was able to make a small contribution to the work!

#nucleoli #ddx21 #RNA

https://doi.org/10.1016/j.cell.2022.12.004