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We focus on the small stuff so you can too: enabling the resolution revolution with high quality support films for cryo-electron microscopy. Part of
@SPTLabtech
Websitehttps://www.quantifoil.com/
Twitter@quantifoil
LinkedInhttps://www.linkedin.com/company/quantifoil
Fantastic #cryoem #cryoet Rotavirus study from @proteincapsid in the Mark Boyce and David Stuart labs @OxfordStrubi. Truly amazing to see the potential of in situ methods to address the dynamic nature of proteins and reveal previously unseen conformations. https://www.cell.com/cell-host-microbe/fulltext/S1931-3128(23)00108-7
Characterization of the rotavirus assembly pathway in situ using cryoelectron tomography

Shah et al. used cryo-tomography to characterize the assembly pathway of rotavirus inside infected cells. The use of flash frozen samples preserved the assembly stages in their native state and relative proportions, and subtomogram averaging revealed their molecular structures, to near atomic detail in the best case.

Cell Host & Microbe
We're excited to be at the #ccpem spring symposium in April and hope to see many of you there. Don't miss the chance to learn about how to access the chameleon sample preparation instrument at SPTLabtech's workshop on Monday, 24th April!
On #cryoem grid #proteinpurification is an exciting application for affinity grids, but how to handle all the sample application and washing on that tiny grid?
Kailash Ramlaul
and others in Chris Aylett's lab
at Imperial College
use a flow cell to overcome these issues in this fab preprint. Congrats! https://t.co/Y9D4vsI73w
The focus of this year's #Internationalwomensday (today!) is on improving women's equality in tech and health. With that in mind, this recent article in New York Times seem particularly relevant. Female mice are traditionally excluded from trials because their hormones make them too erratic. But is that really true?
https://www.nytimes.com/2023/03/07/science/female-mice-hormones.html
Hormones Don’t Affect Behavior of Female Mice, Study Finds

A new study finds male mice more unpredictable than females, challenging century-old assumptions used to exclude females from research because of their hormones.

The New York Times
Thank you to every one who participated in the future of #cryoem sample preparation survey (https://share.hsforms.com/1hbex39XUTJC6YT56bV4dLg3x6g5). Keep your eyes on the post for the next few days!👀👀- we're just shipping the tweezers to our lucky first 48 entrants!
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Delighted to be at #MC2023 in very sunny Darmstadt. Though sadly we can't claim to have come quite as far as our badges suggest: SPTLabtech is based in the rather less famous Melbourn, UK! #cryoem #structuralbiology
We are excited to be at #MC2023 in Darmstadt next week. Join us at booth E1-16a and learn about how SPTLabtechand Quantifoil are driving innovation in #cryoEM sample preparation!
Fantastic to see our SPTLabtech colleagues at #BPS2023. Why not drop in on booth 821 and to hear more about the latest developments in grid technology - and of course our new building! #cryoem #structuralbiology #cryoet
Listening to some great #cryoem talks this evening at the boundary of academia and pharma hosted by CambridgeNTF https://www.camntf.org/. Looking forward to some very interesting discussions over drinks later!
Cambridge New Therapeutics Forum (CamNTF)

Cambridge New Therapeutics Forum (CamNTF) is a local forum to promote interactions between scientists from academia & industry.

Cambridge New Therapeutics Forum
#sampleprep is evolving along with the rest of #cryoem. What improvements would make the most difference to your samples? Fill out this survey and help drive the future of cryoEM sample preparation (and receive a pair of high-quality tweezers as a thank you!). https://share.hsforms.com/1hbex39XUTJC6YT56bV4dLg3x6g5
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