| powered by | https://feed2toot.readthedocs.io |
| sibling of | @bioRxiv_cytoskeleton@botsin.space |
| contact info | @jocelyn_etienne |
@Rxiv_cytoskeleton will disappear, but long live @Rxiv_cytoskeleton ! (me!)
The server @botsin.space is closing down. Thanks @muffinista for having maintained it for so long.
I (= @jocelyn_etienne ) am moving the bots from there to their new home, @biologists.social. Thanks to @Co_Biologists for offering this space !
Report to @jocelyn_etienne any issue in the coming days.
Bots @mechanobio and @flypapers will follow same move.
The cytoskeleton is the major mechanical unit of the cell and is essential for cellular processes such as motility, division, and contraction. It consists of three types of biopolymers-actin filaments, microtubules, and intermediate filaments-along with passive cross-linkers and active motor protein …
During cell division, the network of microtubules undergoes massive rearrangement to self-organize into the spindle, a bipolar structure essential for accurate chromosome segregation. This structure ensures the stable transmission of the genome from the mother cell to two daughter cells, yet the pro …
Nanaomycin K is a natural compound found in the culture broth of "Streptomyces rosa subsp. notoensis" OS-3966. Studies have shown that it inhibits epithelial-mesenchymal transition (EMT), a recognized mechanism of cancer cell migration. Here we investigated the EMT-inhibitory and antitumor effects o …
During asymmetric cell division, cortical polarity cues drive the polarization of the microtubule cytoskeleton to ensure the generation of two daughter cells with different fates. While this a critical process for development and tissue homeostasis, the underlying molecular mechanisms orchestrating …
The centrosome plays a crucial role in facilitating mitotic spindle assembly through its microtubule organizing capacities. Analyzing the composition, structure, and functions of mitotic centrosomes is essential for understanding the mechanisms underlying cell division and centrosome-associated dise …
The bipolar shape of the microtubule-based spindle is a pivotal morphological phenotype for accurate chromosome segregation during cell division. However, existing descriptions of spindle morphogenesis remain largely qualitative. Here, we introduce a method that provides a quantitative description o …
Photoswitchable compounds are potent tools for elucidating molecular functions in dynamic cellular processes. Photoswitchable inhibitors targeting various mitotic spindle factors have been developed. In this chapter, we describe experimental methods for photo-controlling mitotic chromosome dynamics …
Rxiv cytoskeleton