Letzte Woche fand das HIPS Symposium statt, die jährliche wissenschaftliche Konferenz des HIPS am Standort #Saarbrücken. Das Team des Mikrobielle Schatzkiste Projekts war mit dabei und hat #Citizenscience Ergebnisse als Poster präsentiert :) #Saarland https://hips.saarland/sample

Das HIPS bildet aus! Drei Ausbildungsplätze zur Chemielaborant*in und Biologielaborant*in sind aktuell ausgeschrieben, Start zum 1. September. https://hips.saarland/ausbildung

ERC Proof of Concept Grant for Anna Hirsch! The HIPS scientist receives funding to develop new antibiotics. | Press release https://www.helmholtz-hips.de/en/news-events/news/detail/news/erc-proof-of-concept-grant-for-anna-hirsch/

Disarming pathogens - bacterial communication as a target for new drugs. | Towards Translation of PqsR Inverse Agonists: From In Vitro Efficacy Optimization to In Vivo Proof-of-Principle https://doi.org/10.1002/advs.202204443

The team of Alexander Titz at HIPS and collaborators developed novel pathoblockers acting on Lectins to fight infections with Pseudomonas aeruginosa. Read more on our website (English and German version available). https://www.helmholtz-hips.de/en/news-events/news/detail/news/sugar-based-inhibitors-disarm-the-pathogen-pseudomonas-aeruginosa/

📢 Registration is open for our yearly 1-day conference on pharmaceutical sciences devoted to infection research! Check out the list of speakers and join the #HIPS2023 symposium on-site in Saarbrücken/Germany or as a remote participant. https://hips.saarland/symposium

Our study on the myxobacterial antibiotic Myxovalargin including biosynthesis, structural revision, total synthesis, and molecular characterization of ribosomal inhibition now online in JACS. https://pubs.acs.org/doi/10.1021/jacs.2c08816

📢 Registration is now open for our yearly 1-day conference on pharmaceutical sciences devoted to infection research! Join the #HIPS2023 symposium on-site in Saarbrücken/Germany or as a remote participant. More speakers to be announced soon. https://hips.saarland/symposium

Our chemists are also concerned with improvement of #naturalproducts scaffolds using (semi)synthesis: Regio- and Stereoselective Epoxidation and Acidic Epoxide Opening of Antibacterial and Antiplasmodial Chlorotonils Yield Highly Potent Derivatives.
https://doi.org/10.1002/anie.202202816

We are mainly searching for new anti-infective #naturalproducts but we won't look away when we find molecules from #myxobacteria with other striking properties, like in this article - Expanding the Ajudazol Cytotoxin Scaffold: Insights from Genome Mining, Biosynthetic Investigations, and Novel Derivatives. https://doi.org/10.1021/acs.jnatprod.2c00637