Japan/Indonesia/global historian@Leiden University, author of _Japan's Occupation of Java: A Transnational History_, and translator of _Grassroots Fascism: The War Experience of the Japanese People_ (吉見義明の『草の根のファシズム』の英訳); bass, vocals, drums, and percussion; WWII, colonialism & funky music
#histodons #asianists #colonialism
https://www.universiteitleiden.nl/en/staffmembers/ethan-mark#tab-1
https://m.facebook.com/NineteenSeventyEightBand
This coming Monday at Leiden, 15-17, Lipsius 148!
Did you know that there were internment camps in India during World War II? Have you wondered who was incarcerated there? Why do we know so little about their experiences? This presentation explores civilian internment in India through a small cast of characters unwittingly drawn into and implicated…
After Covid-19 infection, 12.5% develops post-Covid-syndrome (PCS). Symptoms indicate numerous affected organ systems. After a year, chronic fatigue, dysautonomia and neurological and neuropsychiatric complaints predominate. In this study, 95 PCS patients were treated with selective serotonin reuptake inhibitors (SSRIs). This study used an exploratory questionnaire and found that two-thirds of patients had a reasonably good to strong response on SSRIs, over a quarter of patients had moderate response, while 10% reported no response. Overall, patients experienced substantial improved well-being. Brainfog and sensory overload decreased most, followed by chronic fatigue and dysautonomia. Outcomes were measured with three different measures that correlated strongly with each other. The response to SSRIs in PCS conditions was explained by seven possible neurobiological mechanisms based on recent literature on PCS integrated with already existing knowledge. Important for understanding these mechanisms is the underlying biochemical interaction between various neurotransmitter systems and parts of the immune system, and their dysregulation in PCS. The main link appears to be with the metabolic kynurenine pathway (KP) which interacts extensively with the immune system. The KP uses the same precursor as serotonin: tryptophan. The KP is overactive in PCS which maintains inflammation and which causes a lack of tryptophan. Finally, potential avenues for future research to advance this line of clinical research are discussed.
