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Very excited that our whole-mouse-brain analysis pipeline - DELiVR - is published now at Nature Methods. With DELiVR, we built an open-source, easy-to-use pipeline for analyzing image stacks from cleared mouse brains.

Paper: https://www.nature.com/articles/s41592-024-02245-2
Code: https://github.com/erturklab/delivr_cfos
Docker containers, test dataset, handbook: https://www.discotechnologies.org/DELiVR/

#neuroscience #tissueclearing #lightsheet #imageanalysis

Virtual reality-empowered deep-learning analysis of brain cells - Nature Methods

Generating training data for training deep-learning-based tools is time consuming. The DELiVR pipeline facilitates this process as demonstrated in this study on detecting c-Fos+ cells or microglia in the brain, following tissue clearing and imaging with light-sheet microscopy.

Nature

Huge thanks to co-first authors @rami and @dorie00, as well as everyone at the Ertürk and Berriel Diaz labs! This was a true team effort, and we couldn't have done it otherwise.

Check out the explainer over on Twitter: https://x.com/erturklab/status/1782363977449611394

Ali Max Erturk (@erturklab) on X

Very excited to share that our DELiVR method is now open access published @NatureMethods. We created a simple, brain-wide cell analysis deep learning tool, no coding needed! Fiji Plugin makes it accessible to all. https://t.co/qjFk3p5aba by @Dorie00 @Rami96614090 @moritz_negwer

X (formerly Twitter)
Speechless 💥💥💥
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RT @erturklab
Imagine you could stain whole adult mice with standard IgG antibodies. What you couldn't do! We present wildDISCO technology for this🤗, creating the first whole body vascular, lymphatic, and nerve atlases. By @HongchengM @jieluo692 https://www.biorxiv.org/content/10.1101/2023.02.17.528921v1.full.pdf 🧵👇🏼(turn on the sound)
https://twitter.com/erturklab/status/1627615842073452544