After 10+ years working with #metabolomics mass-spectrometry data, you would think I wouldn't be surprised any more.
However, I'm surprised every time when a method or tool uses non-log-transformed abundances into a standard t-test or another semi-normal distribution assuming statistical framework. 🤦♂️
Seriously, we need more statistically minded people in #metabolomics / #lipidomics.
https://rmflight.github.io/posts/2021-04-09-proportional-error-in-mass-spectrometry/