BioCyc and Pathway Tools

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This is the official Mastodon account for BioCyc and Pathway Tools, including EcoCyc, MetaCyc and other related sites.

BioCyc is a collection of Pathway/Genome Databases for over 20,000 organisms, plus software tools for exploring them. BioCyc is an encyclopedic reference that contains curated data from 130,000 publications.

Pathway Tools is a comprehensive bioinformatics software package that spans enterprise genome data management, systems biology, and omics analysis.

BioCychttps://biocyc.org
EcoCychttps://ecocyc.org
MetaCychttps://metacyc.org
Pathway Toolshttp://bioinformatics.ai.sri.com/ptools/

Our paper about CyanoCyc and the community curation review project of Synechocystis sp. PCC 6803 substrain Kazusa has just been published in Frontiers in Microbiology: https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2024.1340413/full

Read about how CyanoCyc started in order to address a real need by the research community and how to use some of the powerful bioinformatics tools available with the hundreds of cyanobacterial genome databases.

Frontiers | CyanoCyc cyanobacterial web portal

<p>CyanoCyc is a web portal that integrates an exceptionally rich database collection of information about cyanobacterial genomes with an extensive suite of ...

Frontiers
A new, updated version of the FlyCyc metabolic network is now available as part of BioCyc. FlyCyc represents all the metabolic reactions and pathways of Drosophila melanogaster, computed by combining comprehensive pathway data in MetaCyc with the set of manually curated/reviewed Gene Ontology annotations at FlyBase. FlyCyc was last updated >15 years ago, so this new release includes substantial updates to functional, genomic and nomenclature data. https://tinyletter.com/FlyBase/letters/flybase-fb2023-06-released
FlyBase FB2023_06 Released

= New and Notable Changes in FB2023_06 =

TinyLetter
New paper out today in Metabolites describing the latest features of our Omics Dashboard, including brand new multiomics capabilities! https://www.mdpi.com/2644740
The Omics Dashboard for Interactive Exploration of Metabolomics and Multi-Omics Data

The Omics Dashboard is a software tool for interactive exploration and analysis of metabolomics, transcriptomics, proteomics, and multi-omics datasets. Organized as a hierarchy of cellular systems, the Dashboard at its highest level contains graphical panels for the full range of cellular systems, including biosynthesis, energy metabolism, and response to stimulus. Thus, the Dashboard top level surveys the state of the cell across a broad range of key systems in a single screen. Each Dashboard panel contains a series of X–Y plots depicting the aggregated omics data values relevant to different subsystems of that panel, e.g., subsystems within the biosynthesis panel include amino acid biosynthesis, carbohydrate biosynthesis and cofactor biosynthesis. Users can interactively drill down to focus in on successively lower-level subsystems of interest. In this article, we present for the first time the metabolomics analysis capabilities of the Omics Dashboard, along with significant new extensions to better accommodate metabolomics datasets, enable analysis and visualization of multi-omics datasets, and provide new data-filtering options.

MDPI
Introducing our New Genome Browser:
The new version is much faster--it zooms and pans in real time. New features include the ability to extract sequence regions.
Check it out at https://biocyc.org/genbro/genbro.shtml?orgid=ECOLI&replicon=COLI-K12

Upcoming BioCyc Webinar:
The Comparative Genome Dashboard

May 18, 10am PDT

For more info and registration, see
https://sri.zoomgov.com/meeting/register/vJIsf-ytqTIuGYXu2mLvFN9RXt2D7fABt0E

#bioinformatics #genomics

Meeting Registration - Zoom

#introduction
This is the official account for BioCyc and Pathway Tools. The account is currently being managed by @smpaley. I'll be posting announcements, answering any questions, and boosting relevant posts from members of our team and user community (will follow and engage with posts carrying hashtag #BioCyc).

https://biocyc.org