🔬🔬Microbiology PIs looking for a great way to show your students you care?
Nominate them for the TOP prize in prokaryotic molecular biology, the Nat L. Sternberg Award!
Nominations due May 1, 2023
https://conferences.union.wisc.edu/phages/awards-prizes/sterenberg-thesis-prize/
Bacterial droplet-based single-cell RNA-seq reveals antibiotic-associated heterogeneous cellular states @[email protected]
"BacDrop thus can capture cellular states that cannot be detected by bulk RNA-seq" #microbiology #microbiome #genomics #research
https://www.cell.com/cell/fulltext/S0092-8674(23)00002-8
🐦🔗: https://twitter.com/HostMicrobeLit/status/1619147184884314112
TL;DR Illuminating the mechanisms that underlie biological phenomena requires an understanding of the context in which these phenomena occur. Population studies are important, but mol bio folk want to know what happens in single cells. We hope our model will be helpful!
If you made it this far, THANK YOU! Comments and thoughts on this pandemic labor of love are very welcome!
We used our model to help explain the reduction in elongation rate in fast-growing cells. Our data suggests it is due to be titration of essential substrates/enzymes, & not interference between replication forks on the same chromosome or DNA pol reaching terminal velocity.
We are looking forward to testing this idea and others in lab!
Amelia Randich