Great to see this out! EM12-SO2F engages #CRBN covalently in the IMiD pocket and can be used to efficiently block the #IMiD binding site. We share detailed methods for the synthesis and application #covalent #SuFx #histidine #TPD
Read more here: https://www.sciencedirect.com/science/article/pii/S0076687922003810?dgcid=author

Join us tomorrow for Mikko Taipale #TPDwebinar 12:00 noon EST. Register to join via zoom at https://www.danafarbertargetedproteindegradation.org/