PhilipLeftwich

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278 Following
264 Posts
Biologist/Geneticist |
pest control | insects | microbiome | #GeneDrive |
teaches genetics and #rstats |
likes cats |
he/him
Twitterhttps://twitter.com/PhilipLeftwich
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Scholarhttps://scholar.google.com/citations?hl=en&user=5-qU7lkAAAAJ
Githubhttps://github.com/Philip-Leftwich

1) New paper out! Alternative reproductive tactics and evolutionary rescue—do low-condition males that acquire matings by other means affect the rate of adaptation? Intuitively you'd think yes: some of these males will have poor condition because of maladaptive alleles or a high mutational load, so if the alternative tactic increase the input of their genes into the next generation that should be A Bad Thing

https://academic.oup.com/evlett/advance-article/doi/10.1093/evlett/qrae010/7630433?searchresult=1

Alternative reproductive tactics and evolutionary rescue

Abstract. Almost all life on earth is facing environmental change, and understanding how populations will respond to these changes is of urgent importance. One

OUP Academic
Did you know that SORTEE has a YouTube channel where you can (re)watch the plenaries from our past conferences?
Check it out here: https://youtube.com/@SORTEcoEvo/videos (and don't forget to subscribe and like to help us spread the word 😉) #openscience
Bevor Sie zu YouTube weitergehen

Has there been a meaningful change in the number of black professors in the UK?

https://www.nature.com/articles/d41586-024-00249-8

Nature thinks so, but I think a 25% increase in a single year sounds huge until you look at the tiny numbers involved

Number of Black UK professors rises by 25% in one year

Initiatives such as grass-roots campaigns are likely to have contributed to the uptick, but barriers to progress remain.

A multiplexed, confinable CRISPR/Cas9 gene drive can propagate in caged Aedes aegypti populations - Nature Communications

Aedes aegypti is the main vector of several major pathogens including dengue, Zika and chikungunya viruses. Here the authors find that a CRISPR/Cas9 based split gene drive in Aedes aegypti could successfully bias inheritance up to 89% over successive generations in a multi-cage trial with further deep sequencing suggesting that the multiplexing design could mitigate resistance allele formation.

Nature

I hope you don't need this, but here are some tips on organizing your -80.

https://www.nature.com/articles/d41586-024-00031-w

However, if you are like me, its a good reminder to clear out the 'It's 6:30, and I swore I'd be home at 6:00, but I just finished making this thing' tray in our -80.

Yes, we do have one, and it is useful because sometimes you have something that needs to go in the -80 right now, but you also need GO HOME RIGHT NOW!! Because it's a concrete location, it doesn't get too crazy.

#LabLife

Organize your –80 °C freezer to save time and prevent frozen fingertips

Start the new year by sorting out your lab’s cold storage, to simplify purchasing, improve experiment planning and reduce the frequency of lost samples.

Check out my friend Martin's adventures in bio-sonification. Making music out of the electrical impulses produced by living organisms!
https://revolutionarybiscuits.wordpress.com/
Revolutionary Biscuits

Audio Exploration

Revolutionary Biscuits

New Year, new papers!

Medfly gene drive paper is now out in Nature Comms!

https://www.nature.com/articles/s41467-023-44399-1

Gene drive and genetic sex conversion in the global agricultural pest Ceratitis capitata - Nature Communications

Homing-based gene drives are novel interventions promising the area-wide, species-specific genetic control of harmful insect populations. Here the authors demonstrate the feasibility of a gene drive approach for the genetic control of the agricultural pest, the medfly, based on complete female-to-male sex conversion.

Nature
me too random appliance, me too

🌅 I’m thrilled to announce the launch of Daly Analytics (@dalyanalytics), a data science consulting company specializing in shiny app development, machine learning, predictive analytics & R programming! #rstats

☕️ Let’s chat dalyanalytics.com

Who will be going to PopGroup 57 in St. Andrews next week? I was planning on using BlueSky, but without hashtags such as #PGG57 #Evolution #PopGen, I'm not sure how it will work?