Maurice Lee

@Mauriceylee
97 Followers
92 Following
18 Posts
I build microscopes & write code | he/him |
Biophysics PhD 2019 |
Working on 3D spatial transcriptomics (with MERFISH) with oblique plane lightsheet microscopy
My Google Scholarhttps://scholar.google.com/citations?user=BYjdgGUAAAAJ&hl=en
Current research grouphttp://khchenlab.github.io
Current research institutehttps://www.a-star.edu.sg/gis
Research interests#SpatialTranscriptomics #MERFISH #Lightsheet #Microscopy #SMLM
Maurice LeeAug 16, 2023
"By combining single-cell sequencing with methods to map the spatial location of gene expression, scientists are unravelling the extraordinary cellular diversity of the brain."
https://www.nature.com/articles/d41586-023-02559-9
The quest to map the mouse brain

By combining single-cell sequencing with methods to map the spatial location of gene expression, scientists are unravelling the extraordinary cellular diversity of the brain.

Maurice LeeAug 8, 2023
Dr Waters is searching for an advanced microscopy fellow!
https://microfellows.hms.harvard.edu/apply/
Maurice LeeAug 7, 2023
Yes! I feel like I'm working on a technology of the future now.
"we foresee that spatial omics will likely evolve toward three-dimensional spatial omics (operating on whole organs or even organisms)"
https://www.science.org/doi/10.1126/science.abq4964
Maurice LeeAug 4, 2023
I'm still amazed that my Pixel 7 can see stars with the astrophotography mode amidst all that light pollution in Singapore.
Maurice LeeAug 4, 2023
It was a sunny day at #BiopolisSingapore
Show threadMaurice LeeAug 4, 2023
And the results are in!
The #1.5 glass coverslips that we have are all thicker than the 170 microns I expected. The range is supposed to be 150-190 microns. And different brands of coverslips have slightly different distributions too!
Maurice LeeAug 3, 2023
We finally got a micrometer screw gauge (with a ratchet) to measure the thicknesses of our #1.5 glass coverslips to see how close they are to the specified 0.170 mm thickness with micron precision!
The first two were 0.183 and 0.212 mm thick.🤷🏻‍♂️
Maurice LeeJul 31, 2023

I wonder if I'd notice if an entire scientific field suddenly stop publishing.

Soviet scientist "Flyorov had found that American and British scientists, who regularly had been writing on nuclear developments before mid-1940, had stopped publishing. This, he pointed out in his letter to Stalin, meant "that nuclear research in the United States had now been made secret"

https://www.washingtonpost.com/archive/politics/1979/07/27/soviets-had-chance-to-develop-first-a-bomb-historian-says/49b94c40-d210-459b-89a0-98c9d2109b8f/

Soviets Had Chance to Develop First A-Bomb, Historian Says

Washington Post
Maurice LeeJul 30, 2023
Got a chance to enjoy the hot weather and see some touristy sights in Singapore today!
Maurice LeeJan 25, 2023
Show threadChristophe Leterrier 🔬Jan 25, 2023
And finally, we extend our SD-STORM implementation to simultaneous 3-color imaging. Check the whole preprint here: https://www.biorxiv.org/content/10.1101/2023.01.23.525017v1 Kudos to all authors 🙏🏻 (6/6)