It is nice to see other group reached the same gene target and nicely repeated your work when they took a wildly different approach :)

this cool work from Alex Keene lab attempted to use GWAS to locate Excessive daytime sleepiness locus mapped to "rs2787120-tagged locus and its proxies contacted a dense cluster of 12 genes " and one of them include HPCA
https://www.biorxiv.org/content/10.64898/2026.04.07.715910v1.full

they did a neuronal knockdown in flies and found then same as us (https://doi.org/10.7554/eLife.38114)

#drosophila #sleep #GWAS

Posting the link here for those who aren't on Mastodon: www.biorxiv.org/content/10.6...

biorxiv.org/content/10.648...
Neurocalcin regulates nighttime sleep and arousal in Drosophila

The neuronal calcium sensor Neurocalcin regulates sleep and arousal thresholds during the night in Drosophila.

eLife