Tip: if you're suffering from #EyeStrain looking at an LED or OLED screen, try setting the brightness to 100%.
This is by no means guaranteed to solve your problem, but it might.
The reason it might solve your problem is that a lot of such screens implement less-than-100% brightness by rapidly flickering (technically called #PWM dimming), which some #eyes are sensitive to.
I'm suffering from eye strain myself and I'm not sure yet whether this helps me. We'll see. But maybe it'll help you.
This might not work on OLED screens because they're doing dimming per-subpixel, and unless every pixel on your entire screen is completely monochrome (either full black or full white), some subpixels are going to be somewhere between 0% and 100% brightness anyway.
But it should work on LCDs, where subpixel brightness is controlled separately (by doing things to liquid crystals) from backlight brightness (which is done by the aforementioned flickering).
Some newer screens use DC dimming instead, which achieves less-than-100% brightness without flickering.
This method instead relies on altering the voltage applied to each LED. It's very hard to pull off because different individual LEDs respond to voltage changes differently, so it's highly likely that colors will be all wrong.
But if a screen manufacturer can pull it off, the result is a screen that won't cause flicker-induced eye strain.
In theory, flicker-induced #EyeStrain could also be avoided if the #PWM frequency was much much much higher than it currently is.
According to https://www.notebookcheck.net/Analysis-DC-Dimming-vs-PWM-Can-you-dim-AMOLED-displays-without-the-flickering.423121.0.html the PWM flicker frequency is usually only about 200Hz. This is well within the range of the human #eye, which can sometimes sense light pulses with a frequency as high as 1000Hz.
If the PWM frequency was in the tens of kHz or more, perhaps it wouldn't cause eye strain even in sensitive individuals.
Some smartphone users have a problem: The AMOLED display of their smartphone causes them headaches, because it flickers at low brightness. DC dimming might be a solution for this. We explain the new technology in this article and evaluate the advantages looking at two examples.
There's another reason this might be effective - your pupil size impacts your depth of field, and for the same reason that "squinting" makes it easier to compensate for myopia, smaller pupils make focusing easier. This means that, eg, computing in a dimly lit room is more taxing on the eyes than computing in a well-lit room.
Of course... indoor fluorescent and overhead LED lights also are modulated, often as a side effect of being AC powered, so that flicker can cause problems, too.
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