@irene LDN is on my list of things to try. I don't bother talking to doctors to get prescriptions for anything I think could work that isn't scheduled, it's not worth the hassle; naltrexone is cheap and easily obtainable. can't say how well it works yet, am not in a stable enough position to switch to that from pregabalin/tramadol
the latter combination a specialist told me will make knowledge work for me impossible within 6 months... 3 years ago. I don't think I've acquired any significant cognitive impairment I can attribute to that, nor did I need to increase my dose; but it's definitely a drug combination that... how do I put it, experientially defines your life? not in a bad way, just in a "you're going to plan everything around it now" way.