Ketamine-induced changes in accumbal glutamate and their association with altered states of consciousness (2026) “individual glutamate changes induced by #ketamine correlate with anxious ego dissolution and reductions in vigilance, indicating that ketamine-induced glutamate alterations in the NAc underly specific alterations in perception and consciousness.” https://pubmed.ncbi.nlm.nih.gov/41871813/ #brains #psychedelics
Ketamine-induced changes in accumbal glutamate and their association with altered states of consciousness - PubMed

Ketamine has been shown to modulate glutamate signaling in animals and may therefore have the potential to restore glutamate imbalances in the brain. Impaired glutamate homeostasis has been implicated in mental health disorders such as substance use disorders (SUDs). Thus, we investigated ketamine's …

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