SBGridSBGrid's eLife paper received a citation in February from James Berger from The Johns Hopkins University School of Medicine in Nature Communications: Supercoiled DNA recognition and cleavage control in topoisomerase VI.
Supercoiled DNA recognition and cleavage control in topoisomerase VI - Nature Communications
DNA recognition and cleavage control in type II topoisomerases are poorly understood processes. Here, the authors determine cleaved and uncleaved structures of supercoiled DNA-bound topoisomerase VI that reveal how the enzyme activates its cleavage state and prefers to act at deformable substrates.