Dimethyl fumarate (DMF) is an oral therapy approved for the treatment of relapsing-remitting multiple sclerosis. It is also known to reduce disease severity in experimental autoimmune encephalomyelitis (EAE). Female C57BL/6J mice were immunized with MOG35-55 to induce EAE and treated with DMF (7.5 mg/kg, oral gavage, every 12 h) or vehicle starting at
