@Zarkonnen Depends on the game and why I'm playing. Almost never play to the bitter end though lol.
But if it's my first time running a certain mission I'll definitely hang on longer so I can learn more about what I'm up against. On the other hand, if it's a game I've been playing for years then I probably have something very specific that I'm trying to do on this run so I'm more likely to restart if it doesn't go perfectly (but probably won't bother to save at all if it's a game I've already beaten.) And if I keep losing then I'll start saving more often and reloading the instant something doesn't go as planned, while on my first few runs I'm more likely to keep going if I think I have any chance at all.