The TransmitterJun 19, 2024

The technique, which measures calcium currents as a proxy for neuronal firing, sometimes reports unusual and potentially misleading waves of activity in the hippocampus.

By @avaskham

https://www.thetransmitter.org/methods/widely-used-calcium-imaging-protocol-can-lead-to-spurious-results-new-paper-cautions/?utm_source=mastodon&utm_medium=org-social&utm_campaign=20240619-calcium-imaging

Widely used calcium imaging protocol can lead to spurious results, new paper cautions

The technique, which measures calcium currents as a proxy for neuronal firing, sometimes reports unusual and potentially misleading waves of activity in the…

The Transmitter: Neuroscience News and Perspectives
Show threadAlbert Cardona

@thetransmitter @avaskham

Commentary of:

"Aberrant hippocampal Ca2+ micro-waves following synapsin-dependent adeno-associated viral expression of Ca2+ indicators" by Masala et al. 2024.

https://elifesciences.org/reviewed-preprints/93804v2

#neuroscience #GCaMP #CalciumImaging #artifacts

Aberrant hippocampal Ca2+ micro-waves following synapsin-dependent adeno-associated viral expression of Ca2+ indicators

Jun 19, 2024 at 1:50pmWeb