Lukas VFN 🇪🇺#Protein allows poison dart #frogs to accumulate toxins safely
https://phys.org/news/2023-12-protein-poison-dart-frogs-accumulate.html
Binding and sequestration of poison #frog alkaloids by a plasma globulin https://royalsocietypublishing.org/doi/10.1098/rspb.2023.2177
"In humans, the liver can safely metabolize modest amounts of these compounds. Tiny #PoisonDartFrogs consume far more toxic #alkaloids in their diets, but instead of breaking the #toxins down, they accumulate them in their skin as a defense mechanism against predators."
Protein allows poison dart frogs to accumulate toxins safely, shows study
Scientists have identified the protein that helps poison dart frogs safely accumulate their namesake toxins, according to a study published today in eLife. The findings solve a long-standing scientific mystery and may suggest potential therapeutic strategies for treating humans poisoned with similar molecules.