How big is the #unknome? In other words, how many of the 20,000 or so genes in the human genome are unknown (in function)? Is there a gradient of unknown-ness? A new paper in @PLOSBiology by Rocha and colleagues introduces us to the unknome and then adds some good stuff, which is the least the authors can do after telling us how little we know about human gene function.
https://sfmatheson.blogspot.com/2023/08/the-known-unknowns-of-biology-welcome.html