Stephen Matheson🌵🌲

Lacramioara Bintu from Stanford introducing the first speaker of the conference! She is Prisca Liberali from FMI in Basel, joining us virtually.

"Decoding the design principles of tissue organization"

Model system is intestinal #organoids
#selforganization

#CSSingleCells23

One #stemcell can generate an entire, organized, organoid

#multiplexed #SingleCell analysis of organoids, using to understand #regeneration after intestinal damage

A screen with 400K organoids and 3000 compounds!

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Aug 28, 2023 at 9:21pmWeb
Show threadStephen Matheson🌵🌲Aug 28, 2023

Check out the lab's work: https://liberalilab.org/

They get biopsies from #human patients then can make #organoids from single stem cells, and study development and regeneration of all cell types, with custom culture media they developed (!)

Their #intestinal organoids are very similar to early development, showing fetal gene expression signature

The Liberali Lab

Liberali Lab 

The Liberali Lab