@knutson_brain @PessoaBrain reductionism allowed us to understand that it was not enough to understand Nature above the elementary particle scale.

Thanks, Reductionism.

#ComplexSystems #NetworkScience @neuroscience @complexsystems

https://royalsocietypublishing.org/doi/full/10.1098/rsta.2020.0410

@manlius @knutson_brain @PessoaBrain @neuroscience @complexsystems

I worry that we are getting tangled 😉 in words like reductionism and emergence. Once we acknowledge that nearly any system w/ recurrence and dynamics has emergence, the question is: how to we study the very large space of systems with it (like brains)? @knutson_brain is offering up a proposal that acknowledges some complexity. Anything wrong with it?
@kordinglab @SussilloDavid @sganguli @DrYohanJohn @Neurograce @tyrell_turing

@NicoleCRust
Perhaps one of most confusing parts is to use fMRI as a guide to how the brain works. It's not a terrible technique (I use it as my main technique) but it does not provide a basis to think of most things in the brain.

I think Brian puts to much faith in the contribution computational capabilities of "chunks of brain". My reminder will be coming soon.

@manlius @knutson_brain @neuroscience @complexsystems @kordinglab @SussilloDavid @sganguli @DrYohanJohn @Neurograce @tyrell_turing

@knutson_brain @NicoleCRust @manlius @neuroscience @complexsystems @kordinglab @SussilloDavid @sganguli @DrYohanJohn @Neurograce @tyrell_turing

My goal is a bit different and to understand complex brains, including human ones in evolutionary perspective.

@knutson_brain
But Brian, what we've learned in that little can be concluded from fmri students involving such small numbers. For one estimating mediations is a huge challenge unless you have substantial sample size.

@wandell @NicoleCRust @manlius @neuroscience @complexsystems @kordinglab @SussilloDavid @sganguli @DrYohanJohn @Neurograce @tyrell_turing

@kordinglab
In practice meditation analysis in psychology is a simple "path model" involving 3 pairwise relationships and a couple of critical statical tests. It provides an interesting evaluation of the pairwise relationships but the impact of the results imo are often overblown. Sometimes even causing is inferred!

@knutson_brain @wandell @NicoleCRust @manlius @neuroscience @complexsystems @SussilloDavid @sganguli @DrYohanJohn @Neurograce @tyrell_turing