https://direitohojenoticias.com.br/circuito-dos-cuidados-cnj-realiza-encontro-e-lanca-documentario-sobre-zika/?fsp_sid=54391
Harris County's health department has launched a new online dashboard to track human cases of mosquito-borne illnesses.
#HarrisCounty #HealthScience #Local #News #CityOfHouston #HarrisCountyPublicHealth #Mosquitos #WestNileVirus #ZikaVirus
Uncover how Zika virus stealthily disables our immune defenses, paving the way for innovative treatments and vaccines. #ZikaVirus #Immunology #MedicalResearch
https://geekoo.news/zika-virus-the-silent-saboteur-of-immune-defenses/
Zika virus secretly builds tiny tunnels to infect unborn babies. Penn State scientists reveal how—and why this discovery could stop future infections.
#ZikaVirus #InfectiousDiseases #PublicHealth
https://geekoo.news/tunnel-building-virus-how-zika-secretly-crosses-from-mother-to-fetus/
La melodía de cortejo de las moscas de la fruta podría ser la clave para controlar a los mosquitos
How fruit flies mate may hold a key to limiting the spread of diseases by mosquitoes. In a new study, University of Iowa researchers found a gene that orchestrates the antenna movements of female fruit flies, which is central for them to detect the unique sound produced by prospective male mates.
Fruit flies’ courtship song may hold key to controlling mosquitoes
How fruit flies mate may hold a key to limiting the spread of diseases by mosquitoes
How fruit flies mate may hold a key to limiting the spread of diseases by mosquitoes. In a new study, University of Iowa researchers found a gene that orchestrates the antenna movements of female fruit flies, which is central for them to detect the unique sound produced by prospective male mates.
Protective threshold of a potent neutralizing #Zika virus monoclonal #antibody in rhesus #macaques
Source: Journal of Virology, https://journals.asm.org/doi/full/10.1128/jvi.01429-24?af=R
ABSTRACT
Zika virus (ZIKV) is a mosquito-borne flavivirus that caused a global pandemic in 2016–2017 with continued ongoing transmission at low levels in several countries. In the absence of an approved ZIKV vaccine, neutralizing monoclonal antibodies (mAbs) provide an option for the prevention and treatment of ZIKV infection. Previous studies identified a potent neutralizing human mAb ZIKV-117 that reduced fetal infection and death in mice following ZIKV challenge. In this study, we report exquisite potency of ZIKV-117-LALA-YTE, which has been engineered to reduce Fc receptor binding and to extend half-life, in a titration study in rhesus macaques to protect against ZIKV challenge. We show complete protection at a dose of 0.016 mg/kg ZIKV-117-LALA-YTE, which resulted in median serum concentrations of 0.13 µg/mL. The high potency of this mAb supports its potential clinical development as a novel biotherapeutic intervention for ZIKV.
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#abstract #animalModels #monoclonalAntibodies #research #zikaVirus