How do physiological DNA secondary structures affect genome stability?
In vitro reconstitution by Gideon Coster and coworkers at ICR London shows that a single physiological #G4 or iM #quadruplex formed during #replication stalls the eukaryotic #replisome by inhibiting leading strand synthesis
https://www.embopress.org/doi/full/10.15252/embj.2023114334
In vitro reconstitution by Gideon Coster and coworkers at ICR London shows that a single physiological #G4 or iM #quadruplex formed during #replication stalls the eukaryotic #replisome by inhibiting leading strand synthesis
https://www.embopress.org/doi/full/10.15252/embj.2023114334