Scientists discover novel way to attack the trypanosome parasite through its ribosome

Trypanosome is a single-celled parasite that takes an extensive human and economic toll due to its involvement in causing sleeping sickness in humans and a similar disease in cattle. The parasite, found mainly in rural areas of Africa, is transmitted to humans or cattle by the tsetse fly. There is no vaccine for the disease, and current treatments are difficult and ineffective due to the resistance of the parasites to existing drugs.

Phys.org
Biocatalytic synthesis of pseudouridine for cheaper mRNA vaccines

Researchers from the Institute of Biotechnology and Biochemical Engineering at TU Graz and the Austrian Center of Industrial Biotechnology (ACIB) have developed a novel method for the production of central components of mRNA vaccines and applied for a patent.

Phys.org
TFW you get cited by a crackpot pharmacist in Florida, USA. We actually didn't show an increase in stability of the resulting synthetic mRNA so they don't even reference it properly. #citation #mRNA #RNA #pseudouridine #biology