Couldn’t wait to share - SQUARNA 2.0 is here, with greatly improved performance in single-sequence RNA secondary structure prediction!

https://github.com/febos/SQUARNA

Updated preprint is coming soon :)

#SQUARNA #RNA #2D #Structure #Prediction #Bioinformatics #Research #Pseudoknot

#introduction
Hi, I’m Jill and I collaborate with researchers to develop #RNA modeling puzzles for the science game Eterna.

Our current project asks players around the world to submit sequences up to 90 nt that may fold into a #pseudoknot. The structure will be verified by SHAPE testing at the Das Lab (Stanford). We hope to generate a large dataset containing thousands of pseudoknot and tertiary structures that researchers can use to train new #RNAmodeling algorithms.