Biology OpenHere, Ming-Hsuan Wen et al (University of Cambridge) show that nuclear reprogramming is present in meiotic oocytes and does not require cell division.
“A major difference between oocyte nuclear transfers and iPSC approach concerns the timing of the changes induced.”
#meiosis #nuclearreprogramming #stemcells #therapy #OpenAccess #BiologyOpen
Deterministic nuclear reprogramming of mammalian nuclei to a totipotency-like state by Amphibian meiotic oocytes for stem cell therapy in humans
Summary: Stem cell therapy has shed light on incurable diseases. We describe a novel method for cell reprogramming and provide personalized stem cell sources for stem cell therapies.