Clinical trial: Measurement Properties of the Walking Adaptability Ladder Test and Foot Tap Test in People With Multiple Sclerosis With Mild Disability

https://clinicaltrials.gov/study/NCT07505355?utm_source=fediverse&utm_medium=mastodon&utm_content=trial_20349

#ClinicalTrials #MultipleSclerosis #MSchat #Neurology

https://gregory-ms.com/articles/314427/?utm_source=fediverse&utm_medium=mastodon&utm_content=article_314427

Huazhuo decoction (HD) has been shown to ameliorate disease progression in MS patients, but the underlying mechanisms remain poorly understood. This study assessed the therapeutic efficacy of HD in an experimental autoimmune encephalomyelitis (EAE) model of MS. HD alleviated neurobehavioral impairment, inflammatory infiltration and demyelination in EAE mice.

#MultipleSclerosis #MSchat #MS #Neurology

https://gregory-ms.com/articles/314452/?utm_source=fediverse&utm_medium=mastodon&utm_content=article_314452

Vitamin A or retinoic acid (RA) solution was injected into the abdominal cavities of mice. Retinol promotes self-renewal of embryonic stem cells in vitro culture. It also promotes orientational development of neural stem cells and downregulates the expression of some RA receptor gene expression in the brain.

#MultipleSclerosis #MSchat #MS #Neurology

Clinical trial: An Open-label Study to Evaluate Pharmacokinetics, Safety, Tolerability, Immunogenicity and Pharmacodynamic Effects of Subcutaneous Ocrelizumab Administration in Children and Adolescents With Relapsing-remitting Multiple Sclerosis

https://clinicaltrials.gov/study/NCT07503340?utm_source=fediverse&utm_medium=mastodon&utm_content=trial_20338

#ClinicalTrials #MultipleSclerosis #MSchat #Neurology

Clinical trial: A Phase 2, Multicenter, Study to Evaluate the Pharmacokinetics and Safety of Subcutaneous Ublituximab Administered at Various Injection Sites and Relative Bioavailability Via Autoinjector Device Versus Syringe in Patients With Multiple Sclerosis

https://clinicaltrials.gov/study/NCT07503873?utm_source=fediverse&utm_medium=mastodon&utm_content=trial_20339

#ClinicalTrials #MultipleSclerosis #MSchat #Neurology

Clinical trial: Does Remotely Delivered Pilates Influence Physical and Psychological Outcomes in Individuals With Multiple Sclerosis?

https://clinicaltrials.gov/study/NCT07504120?utm_source=fediverse&utm_medium=mastodon&utm_content=trial_20340

#ClinicalTrials #MultipleSclerosis #MSchat #Neurology

Clinical trial: Clinical Efficacy of a teLerehabilItation Protocol, for the Improvement of Balance in Degenerative neurOlogical Diseases

https://clinicaltrials.gov/study/NCT07502066?utm_source=fediverse&utm_medium=mastodon&utm_content=trial_20326

#ClinicalTrials #MultipleSclerosis #MSchat #Neurology

Clinical trial: A Randomized Controlled Trial of a Low Histamine-Based Modified Mediterranean Diet in Multiple Sclerosis: The Effect of Dietary Interventions on Clinical Findings, Plasma Histamine, and Oxidative Stress

https://clinicaltrials.gov/study/NCT07501520?utm_source=fediverse&utm_medium=mastodon&utm_content=trial_20327

#ClinicalTrials #MultipleSclerosis #MSchat #Neurology

Clinical trial: Skeletal Muscle Aging and Responsiveness in Aged People With MS

https://clinicaltrials.gov/study/NCT07500727?utm_source=fediverse&utm_medium=mastodon&utm_content=trial_20328

#ClinicalTrials #MultipleSclerosis #MSchat #Neurology

https://gregory-ms.com/articles/314226/?utm_source=fediverse&utm_medium=mastodon&utm_content=article_314226

Zolmitriptan is a 5-HT1B/1D receptor agonist that promotes myelination and ameliorates motor dysfunction in Tr-Ncnp mice.

#MultipleSclerosis #MSchat #MS #Neurology