The African natural product knipholone anthrone and its analogue anthralin (dithranol) enhance HIV-1 latency reversal - PubMed

A sterilizing or functional cure for HIV is currently precluded by resting CD4⁺ T cells that harbor latent but replication-competent provirus. The "shock-and-kill" pharmacological ap-proach aims to reactivate provirus expression in the presence of antiretroviral therapy and target virus-e …