Restricted Blood Flow Supercharges Cancer Growth, Study Finds

Restricted blood flow speeds tumor growth by aging the immune system. The findings highlight risks for patients with vascular disease and potential new therapies. A new study from NYU Langone Health reports that restricted blood flow can accelerate the aging of bone marrow, reducing the immune sy

Zeman colpito da ischemia e ricoverato d'urgenza in ospedale: le sue condizioni non sono gravi

Paura per il tecnico boemo Zdenek Zeman, allenatore originario della Repubblica Ceca attualmente alla guida del Pescara, in Serie C: questa mattina ha accusato un malore prima della seduta di allenamento. Accertamenti hanno rilevato una lieve ischemia transitoria. Il tecnico è quindi stato ricoverato presso la clinica Pierangeli di Pescara. Zeman colpito da ischemia, la società rassicura

Reperfusion injury on computed tomography following endovascular revascularization of acute mesenteric ischemia: prevalence, risk factors, and patient outcome - Insights into Imaging

Background Data about reperfusion injury (RI) following acute arterial mesenteric ischemia (AAMI) in humans are scarce. We aimed to assess the prevalence and risk factors of RI following endovascular revascularization of AMI and evaluate its impact on patient outcomes. Methods Patients with AAMI who underwent endovascular revascularization (2016–2021) were included in this retrospective cohort. CT performed < 7 days after treatment was reviewed to identify features of RI (bowel wall hypoattenuation, mucosal hyperenhancement). Clinical, laboratory, imaging, and treatments were compared between RI and non-RI patients to identify factors associated with RI. Resection rate and survival were also compared. Results Fifty patients (23 men, median 72-yrs [IQR 60–77]) were included, and 22 were diagnosed with RI (44%) after a median 28 h (22–48). Bowel wall hypoattenuation and mucosal hyperenhancement were found in 95% and 91% of patients with post-interventional RI, respectively. Patients with RI had a greater increase of CRP levels after endovascular treatment (p = 0.01). On multivariate analysis, a decreased bowel wall enhancement on baseline CT (HR = 8.2), an embolic cause (HR = 7.4), complete SMA occlusion (HR = 7.0), and higher serum lactate levels (HR = 1.4) were associated with RI. The three-month survival rate was 78%, with no difference between subgroups (p = 0.99). However, the resection rate was higher in patients with RI (32% versus 7%; p = 0.03). Conclusion RI is frequent after endovascular revascularization of AAMI, especially in patients who present with decreased bowel wall enhancement on pre-treatment CT, an embolic cause, and a complete occlusion of the SMA. However, its occurrence does not seem to negatively impact short-term survival.

Encefalopatia anossico-ipertensiva e ipercapnia nelle malattie polmonari&nbsp;(ipercarbia)

Ischemia: cos&#8217;è, cause, conseguenze, rischi,&nbsp;cure

Officials say Pfizer's bivalent COVID shot may be linked to stroke

U.S. drugmaker Pfizer Inc and German partner BioNTech's updated COVID-19 shot could be linked to a type of brain stroke in older adults, the CDC and FDA reported.